What is meant by the words “subclinical toxicity”?

Denise Stephens, ZOI CEO (00:00):

Dr. Nicholas, I'm going to start off with what I think is my very favorite quote that you say so many times. It really, it really hit me right between the eyes and you, and I will quote you, you say detoxing should no longer be considered an option. The need for detoxing may be ignored because chronic subclinical toxicity is unseen unfelt and not obvious when it does become obvious after clinical symptoms appear. At that point, it may be too difficult to overcome so many times Dr. Nicholas people are like, what does subclinical toxicity mean? Can you explain that to our friends, please,

Dr. Nikolaos Tsirikos-Karapanos, PharmD, MD, Cardiothoracic Surgeon (00:44):

Denise, I apologize for using so, so much medical terminology and technical scientific technical terminology. But as you know, we treat our technology as if it was a pharmaceutical product. So we can, we try to make it as simple as it can be, but we cannot eliminate the terminology. So now in general and nonvisible problem is a very bad problem. Look at coronavirus. It is transmitted by people who don't have symptoms. So huge problem compared to other diseases that are transmitted only when the carrier has symptoms right now, a fire it's a big problem, but everybody can see the fire. Okay. The worst problems are the invisible ones and that's in general. Now let's discuss what subclinical means in medical sciences and pharmaceutical sciences. Sub-Clinical condition of something means that this something, which is a problem has not yet created clinical symptoms and you don't feel it.

Dr. Nikolaos Tsirikos-Karapanos, PharmD, MD, Cardiothoracic Surgeon (02:12):

Okay. It, it it's something that goes wrong in the background, but there are no clinical manifestations yet allow me, allow me for a second to answer from the point of view of my cardiovascular surgery, a part of life, someone today has a heart attack. All right? And then tomorrow, maybe this person, we need a bypass surgery, which is my field of expertise in, in surgery. Well, the person that today had the heart attack yesterday afternoon, yesterday morning, even today, earlier before the heart attack, this person was considered to be a healthy person, person, no clinical symptom. And then suddenly this afternoon, this person had an acute myocardial infarction, well the stenosis, in the coronary artery or coronary arteries of this individual did not occur from yesterday to today. Actually this the stenosis occurred in the course of the last 10, 15 years. Well, throughout all this period of time of 10 or 15 years, this person had coronary artery disease, but it was subclinical silent.

Dr. Nikolaos Tsirikos-Karapanos, PharmD, MD, Cardiothoracic Surgeon (03:53):

And this means subclinical, unfortunately, toxicity with heavy metals and many other toxins runs a long course, us as sub-clinical condition, a condition that is working in the background every single day, but without the individual having loud symptoms, that would be worried that something goes wrong and we'll go to the doctor. That means subclinical the problem with toxicity of heavy metals and other organic toxins is that once it becomes toxicity, clinical toxicity with clinical manifestations, as we call it in medicine and symptoms, then it is very, very difficult to reverse it. That is the meaning of subclinical chronic subclinical toxicity.

Denise Stephens, ZOI CEO (04:53):

You know, you summed that up very well. Subclinical equals silent. It's not known so, wow, thank you, Dr. Nicholas, what a beautiful explanation. And you know, sometimes those, those bigger words can confuse us, but at the root of it, you do a great job of breaking it down.