In the body, where do toxins predominantly tend to accumulate? Why do they have an affinity to hide there?

Denise Stephens, ZOI CEO (00:00):

Susan. It's your turn. I believe you've got another great question.

ZOI Advisor (00:04):

Yes ma'am thank you. I actually, I wanted to kind of let's stay on where toxins are and that kind of thing. So in the body, where do toxins tend to predominantly accumulate and why do they tend to want to be there? A lot of people ask and they don't think that they know we already talked about getting outside the gut. So where, where are they embedded and why?

Dr. Nikolaos Tsirikos-Karapanos, PharmD, MD, Cardiothoracic Surgeon (00:28):

Very nice. Very nice question, Susan, thank you very much for bringing these. First of all, these toxins that we're talking about, inorganic molecules, inorganic toxins, like heavy metals or organic toxins, herbicides, pesticides, clay mold. At a water soluble herbicides and pesticides are water soluble because they need to be absorbed by the plants. The problem is that being water soluble, they are absorbed by our gut and then they are in circulation. Now based on the certain affinity, as we call it, which is the outcome or the result of certain physical chemical characteristics that toxins have. Not the same for every toxin. Okay. They distribute after they are in the circulation, after being absorbed in the gut they are in circulation, and then they are distributed. Now let's not get this wrong. These toxins go everywhere that we have cells. Or let me put it in a reverse way, there is no place that these toxins don't go. They go everywhere. All right, qualitatively, they're distributed everywhere. Quantitatively, the affinity of the toxins that we're discussing today is sad that predominantly accumulate in the brain, in the fatty tissue, the adipose tissue and the bones. But this is just quantitatively because of their affinity, right?

Denise Stephens, ZOI CEO (02:19):

So they love the bone. They love the brain. They love the fat, predominantly. But they have the ability to go anywhere they decide that they want to go. 

Dr. Nikolaos Tsirikos-Karapanos, PharmD, MD, Cardiothoracic Surgeon (02:29):

They go everywhere. 

Denise Stephens, ZOI CEO (02:35):

Interesting. Thank you. Thank you, Susan. What a great question. You know, and, so we wonder about the fogginess and the stiffness and the various things that affect us as we get older. You see what I'm saying?